工作经历 2001年王俊杰教授率先将放射性粒子组织间近距离引入中国，并通过CT引导、3D打印模板和激光导航技术将放射性粒子植入治疗肿瘤的精度大大提高，成为可普及、可推广的标准化技术，临床治疗达到消融目的，技术普及推广到1000多家医院，培养进修医生3000名。 科研工作 曾经主持过的和在研的项目： 学术兼职 中华医学会放射肿瘤治疗学分会第十届委员会主任委员 中国核学会近距离治疗与智慧放疗分会第一届理事长 中华放射医学与防护杂志副主编 美国 Brachytherapy 杂志编委 获奖情况 2006年获得北京市百名优秀青年医师奖 2009年获得建国60周年北京放射肿瘤专业委员会领军人物奖 2012年教育部科技进步二等奖 2013年华夏医学三等奖 2019年获得第三届国之名医-卓越建树奖。 论文 近五年主要科研成果，按发表时间顺序排列（2016-2021）： 1: Li C, Xu X, Wei S, Jiang P, Xue L, Wang J ; Senior Correspondence. Tumor-associated macrophages: potential therapeutic strategies and future prospects in cancer. J Immunother Cancer. 2021 Jan;9(1):e001341. doi: 10.1136/jitc-2020-001341. PMID: 33504575. 2: Jiang, Y., Zhen, P., Dai, J., Li, Y., Liu, S., Xu, J., Wang, J . (2021). Long-Term Safety and Efficacy of CT-Guided I(125) Radioactive Seed Implantation as a Salvage Therapy for Recurrent Head and Neck Squamous Carcinoma: A Multicenter Retrospective Study. Front Oncol, 11, 645077. doi:10.3389/fonc.2021.645077. PMID: 34277401; PMCID: PMC8281320 3: Jiang W, Chen Y, Ji Z, Jiang Y, Qiu B, Sun H, Wang J . The accuracy and dosimetric analysis of 3D-printing non-coplanar template-assisted iodine-125 seed implantation for recurrent chest wall cancer. J Contemp Brachytherapy. 2021 Jun;13(3):273-279. doi: 10.5114/jcb.2021.106250. Epub 2021 May 18. PMID: 34122566; PMCID: PMC8170518. 4: Xue H, Qiu B, Wang H, Jiang P, Sukocheva O, Fan R, Xue L, Wang J . Stereotactic Ablative Brachytherapy: Recent Advances in Optimization of Radiobiological Cancer Therapy. Cancers (Basel). 2021 Jul 12;13(14):3493. doi: 10.3390/cancers13143493. PMID: 34298703; PMCID: PMC8304109. 5: Wang L, Wang H, Jiang Y, Ji Z, Guo F, Jiang P, Qiu B, Sun H, Fan J, Li W, Wang J . Dosimetric comparison of computed tomography-guided iodine-125 seed implantation assisted with and without three-dimensional printing non-coplanar template in locally recurrent rectal cancer: a propensity score matching study. J Contemp Brachytherapy. 2021 Feb;13(1):18-23. doi: 10.5114/jcb.2021.103582. Epub 2021 Feb 18. PMID: 34025732; PMCID: PMC8117706. 6: Yuan ZH, Liu T, Wang H, Xue LX, Wang JJ . Fatty Acids Metabolism: The Bridge Between Ferroptosis and Ionizing Radiation. Front Cell Dev Biol. 2021 Jun 24;9:675617. doi: 10.3389/fcell.2021.675617. PMID: 34249928; PMCID: PMC8264768. 7: Qiu B, Jiang Y, Ji Z, Sun H, Fan J, Li W, Shao Y, Jiang P, Wang J . The Accuracy of Individualized 3D-Printing Template-Assisted I 125 Radioactive Seed Implantation for Recurrent/Metastatic Head and Neck Cancer. Front Oncol. 2021 Mar 31;11:664996. doi: 10.3389/fonc.2021.664996. PMID: 33869069; PMCID: PMC8045752. 8: Wang H, Peng R, Li X, Wang Y, Jiang Y, Ji Z, Guo F, Tian S, Sun H, Fan J, Wang J . The dosimetry evaluation of 3D printing non-coplanar template-assisted CT-guided 125I seed stereotactic ablation brachytherapy for pelvic recurrent rectal cancer after external beam radiotherapy. J Radiat Res. 2021 May 12;62(3):473-482. doi: 10.1093/jrr/rraa144. PMID: 33616168; PMCID: PMC8127672. 9: Qiu B, Jiang P, Ji Z, Huo X, Sun H, Wang J . Brachytherapy for lung cancer. Brachytherapy. 2021 Mar-Apr;20(2):454-466. doi: 10.1016/j.brachy.2020.11.009. Epub 2020 Dec 24. PMID: 33358847. 10: Liu Y, Jiang P, Zhang H, Wang J . Safety and efficacy of 3D-printed templates assisted CT-guided radioactive iodine-125 seed implantation for the treatment of recurrent cervical carcinoma after external beam radiotherapy. J Gynecol Oncol. 2021 Mar;32(2):e15. doi: 10.3802/jgo.2021.32.e15. Epub 2020 Nov 25. PMID: 33300313; PMCID: PMC7930458. 11: Jiang W, Jiang P, Wei S, Jiang Y, Ji Z, Sun H, Fan J, Li W, Shao Y, Wang J . The accuracy and safety of CT-guided iodine-125 seed implantation assisted by 3D non-coplanar template for retroperitoneal recurrent carcinoma. World J Surg Oncol. 2020 Nov 25;18(1):307. doi: 10.1186/s12957-020-02087-0. PMID: 33239023; PMCID: PMC7690097. 12: Wei S, Wang J . How to manage tumour radiotherapy during COVID-19 pandemic? Eur J Cancer Care (Engl). 2020 Sep;29(5):e13288. doi: 10.1111/ecc.13288. PMID: 32991057; PMCID: PMC7536973. 13: Wang L, Wang H, Jiang Y, Ji Z, Guo F, Jiang P, Li X, Chen Y, Sun H, Fan J, Li W, Li X, Wang J . The efficacy and dosimetry analysis of CT-guided 125 I seed implantation assisted with 3D-printing non-co-planar template in locally recurrent rectal cancer. Radiat Oncol. 2020 Jul 25;15(1):179. doi: 10.1186/s13014-020-01607-2. PMID: 32711542; PMCID: PMC7382046. 14: Li C, Jiang P, Wei S, Xu X, Wang J . Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects. Mol Cancer. 2020 Jul 17;19(1):116. doi: 10.1186/s12943-020-01234-1. PMID: 32680511; PMCID: PMC7367382. 15: Wang H, Li X, Peng R, Wang Y, Wang J . Stereotactic ablative radiotherapy for colorectal cancer liver metastasis. Semin Cancer Biol. 2021 Jun;71:21-32. doi: 10.1016/j.semcancer.2020.06.018. Epub 2020 Jul 3. PMID: 32629077. 16: Gong Y, Yang J, Wang Y, Xue L, Wang J . Metabolic factors contribute to T-cell inhibition in the ovarian cancer ascites. Int J Cancer. 2020 Oct 1;147(7):1768-1777. doi: 10.1002/ijc.32990. Epub 2020 Apr 25. PMID: 32208517; PMCID: PMC7496064. 17: Jiang P, Zhang X, Jiang W, Meng N, Aili A, Wang J . Analysis of long-term outcome of image-guided volumetric modulated arc therapy (VMAT) for primary malignant tumor of the cervical spine. Cancer Biol Ther. 2020 Jul 2;21(7):623-628. doi: 10.1080/15384047.2020.1743149. Epub 2020 Apr 16. PMID: 32298199; PMCID: PMC7515497. 18: Chen Y, Jiang Y, Ji Z, Jiang P, Xu F, Zhang Y, Zhang P, Guo F, Li X, Sun H, Lei R, Fan J, Li W, Huang Y, Wang J . Dosimetry, efficacy, and safety of three-dimensional printing noncoplanar template-assisted and CT-guided 125 Iseed implantation for recurrent retroperitoneal lymphatic metastasis afterexternal beam radiotherapy. Brachytherapy. 2020 May-Jun;19(3):380-388. doi:10.1016/j.brachy.2020.02.009. Epub 2020 Apr 2. PMID: 32249183. 19: Chen Y, Zhuang H, Wang J . The rationale and toxicity of combined cranial radiotherapy and immune checkpoint inhibitors in non-small cell lung cancer. Asia Pac J Clin Oncol. 2020 Mar 4. doi: 10.1111/ajco.13327. Epub ahead of print. PMID: 32129944. 20: Wang H, Wang L, Jiang Y, Ji Z, Guo F, Jiang P, Li X, Chen Y, Sun H, Fan J, Du G, Wang J . Long-Term Outcomes and Prognostic Analysis of Computed Tomography-Guided Radioactive 125 I Seed Implantation for Locally Recurrent Rectal Cancer After External Beam Radiotherapy or Surgery. Front Oncol. 2021 Jan 21;10:540096. doi: 10.3389/fonc.2020.540096. PMID: 33552943; PMCID: PMC7859443. 21: Qiu B, Aili A, Xue L, Jiang P, Wang J . Advances in Radiobiology of Stereotactic Ablative Radiotherapy. Front Oncol. 2020 Aug 7;10:1165. doi: 10.3389/fonc.2020.01165. PMID: 32850333; PMCID: PMC7426361. 22: Wen J, Xiong K, Aili A, Wang H, Zhu Y, Yu Z, Yao X, Jiang P, Xue L, Wang J . PEX5, a novel target of microRNA-31-5p, increases radioresistance in hepatocellular carcinoma by activating Wnt/β-catenin signaling and homologous recombination. Theranostics. 2020 Apr 6;10(12):5322-5340. doi: 10.7150/thno.42371. PMID: 32373215; PMCID: PMC7196300. 23: Qiu YY, Zhang KX, Ye X, Zhang XS, Xing C, Wu QS, Hu MM, Li PX, Wang JJ . Combination of Microwave Ablation and Percutaneous Osteoplasty for Treatment of Painful Extraspinal Bone Metastasis. J Vasc Interv Radiol. 2019 Dec;30(12):1934-1940. doi: 10.1016/j.jvir.2019.08.008. Epub 2019 Oct 24. PMID: 31669085. 24: Chen Y, Jiang Y, Ji Z, Jiang P, Xu F, Zhang Y, Guo F, Peng R, Li X, Sun H, Lei R, Fan J, Li W, Wang J . Efficacy and safety of CT-guided 125 I seed implantation as a salvage treatment for locally recurrent head and neck soft tissue sarcoma after surgery and external beam radiotherapy: A 12-year study at a single institution. Brachytherapy. 2020 Jan-Feb;19(1):81-89. doi: 10.1016/j.brachy.2019.09.006. Epub 2019 Oct 22. PMID: 31653566. 25: Ji Z, Jiang Y, Guo F, Peng R, Sun H, Fan J, Xu F, Wang J . Safety and efficacy of CT-guided radioactive iodine-125 seed implantation assisted by a 3D printing template for the treatment of thoracic malignancies. J Cancer Res Clin Oncol. 2020 Jan;146(1):229-236. doi: 10.1007/s00432-019-03050-7. Epub 2019 Oct 19. PMID: 31630263. 26: Ji Z, Jiang Y, Guo F, Peng R, Sun H, Wang P, Fan J, Wang J . Radiation-related Adverse Effects of CT-guided Implantation of 125 I Seeds for Thoracic Recurrent and/or Metastatic Malignancy. Sci Rep. 2019 Oct 15;9(1):14803. doi: 10.1038/s41598-019-51458-5. PMID: 31616052; PMCID: PMC6794248. 27: Li C, Wei S, Xu X, Jiang Y, Xue L, Jiang P, Wang J . Sorafenib attenuated the function of natural killer cells infiltrated in HCC through inhibiting ERK1/2. Int Immunopharmacol. 2019 Nov;76:105855. doi: 10.1016/j.intimp.2019.105855. Epub2019 Aug 28. PMID: 31472321. 28: Ji Z, Sun H, Jiang Y, Guo F, Peng R, Fan J, Wang J . Comparative study for CT-guided 125 I seed implantation assisted by 3D printing coplanar and non-coplanar template in peripheral lung cancer. J Contemp Brachytherapy. 2019 Apr;11(2):169-173. doi: 10.5114/jcb.2019.84503. Epub 2019 Apr 29. PMID: 31139226; PMCID: PMC6536142. 29: Qu A, Jiang P, Sun H, Jiang W, Jiang Y, Tian S, Wang J . Efficacy and dosimetry analysis of image-guided radioactive 12I seed implantation as salvage treatment for pelvic recurrent cervical cancer after external beam radiotherapy. J Gynecol Oncol. 2019 Jan;30(1):e9. doi: 10.3802/jgo.2019.30.e9. Epub 2018 Oct 30. PMID: 30479093; PMCID: PMC6304405. 30: Jiang P, Wang J , Ran W, Jiang Y, Tian S, Sun H. Five-year outcome of ultrasound-guided interstitial permanent 125 I seeds implantation for local head and neck recurrent tumors: a single center retrospective study. J Contemp Brachytherapy. 2019 Feb;11(1):28-34. doi: 10.5114/jcb.2019.83336. Epub 2019 Feb 28. PMID: 30911307; PMCID: PMC6431107. 31: Zhang S, Yang R, Shi C, Li J, Zhuang H, Tian S, Wang J . Noncoplanar VMAT for Brain Metastases: A Plan Quality and Delivery Efficiency Comparison